谢建武

作者:来源:发布时间:2017-04-14

个人简介

谢建武,男,1978年12月出生,广西壮族自治区博白县人,现为浙江师范大学化学与生命科学学院教授、硕士生导师


学习经历

1997.9-2001.7  广西师范大学化学化工学院获理学学士,化学教育专业

2001.9-2004.7  广西师范大学大学化工学院获硕士学位,有机化学专业

2004.9-2007.7  中国科学院成都有机所获理学博士学位,有机化学专业

2007.4-2008.4  日本京都大学药学部,COE研究员


工作简历

2008.7-至今    浙江师范大学化学与生命科学学院任教

讲师(2008.9)/教授(2010.12)/硕导(2008.12)


人才梯队、荣誉

浙江省“新世纪151人才工程”第三层次培养人员(2009)

省高校中青年学科带头人(2013)

浙江师范大学优秀青年骨干教师(2008)。


研究领域及成果

长期从事不对称有机合成的研究工作。先后在Angew. Chem. Int. Ed.、Chem.Commun.Org. Lett.、J. Org. Chem.、Tetrahedron Lett.、Org. Biomol. Chem.Adv. Synth. Catal.Tetrahedron等国内外学术期刊上发表SCI收录论文30余篇,文章总引用大于500次,单篇引用超过100次有2篇。其中(1)不对称催化1,3-偶极环加成反应研究(Tetrahedron Lett. 2008, 49, 6910-6913)被德国化学评论期刊 SYNFACTS作为有机合成亮点工作进行评述,认为“提供了一条非金属催化合成光学纯的具有药用价值的多个手性中心的吡咯烷衍生物”。

代表性论文、论著

1. T. Shi, Z. Guo, H. Yu, J.-W. Xie*, Y. Zhong, W. Zhu*,Highly Atom-Economic Synthesis of Optically Active Warfarin Anticoagulant over a Chiral MOF Organocatalyst, Adv. Synth. Catal., 2013, 355, 2538-2543.

2.Z.-W. Guo, X.-S. Li, W.-D. Zhu, J.-W. Xie,* Construction of Chiral Multi-functionalized Polyheterocyclic Benzopyran Derivatives by Using an Asymmetric Organocatalytic Domino Reaction, Eur. J. Org. Chem., 2012, 6924–6932.

3.Y.-R. Zhang, J.-W. Xie*, X.-J. Huang, W.-D. Zhu*, Construction of Functionalized 2,3-Dihydro-1,4-Benzoxazines via [5 + 1] Annulations of 2-Halo-1,3-Dicarbonyl Compounds with Imines, Org. Biomol. Chem. 2012, 10, 6554-6561.

4. P. Li, B.-T. Teng, F.-G. Jin, X.-S. Li, W.-D. Zhu, J.-W. Xie*, Synthesis of Functionalized 2,3-Dihydroisoxazoles by Domino Reactions in Water and Unexpected Ring-Opening Reactions of 2,3-Dihydroisoxazoles, Org. Biomol. Chem., 2012, 10, 244-247.

5. Q.-B. Li, F.-T., Zhou, Z.-G. Liu, X.-F. Li, W.-D. Zhu, J.-W. Xie*, K2CO3-Promoted Domino Reactions: Construction of Functionalized 2,3-Dihydrobenzofurans and Clofibrate Analogues, J. Org. Chem. 2011, 76, 7222-7228.

6. L.-P Fan, P. Li, X.-S. Li, D.-C. Xu, M.-M. Ge, W.-D. Zhu, J.-W. Xie*, Facile Domino Access to Chiral Mono-, Bi- and Tricyclic 2,3-Dihydrofurans, J. Org. Chem. 2010, 75, 8716-8719.

7. J.-W. Xie*, X. Huang, L.-P. Fan, D.-C. Xu, X.-S. Li, H. Su, Y.-H. Wen, “Efficient Method for  the Synthesis of Optically Active 2-Amino-2-Chromene Derivatives via One-Pot Tandem Reaction”, Adv. Synth. Catal., 2009, 351, 3077-3082.

8. J.-W. Xie, L. Yue, W. Chen, W. Du, J. Zhu, J.-G. Deng, and Y.-C. Chen, "Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to, α,β-Unsaturated Ketones", Org. Lett., 2007, 9, 413-415.

9. J.-W. Xie, W. Chen, R. Li, M. Zeng, W. Du, L. Yue, Y.-C. Chen, Y. Wu, J. Zhu, and J.-G. Deng, "Highly Asymmetric Michael Addition to a,β-Unsaturated Ketones Catalyzed by 9-Amino-9-deoxyepiquinine", Angew. Chem. Int. Ed, 2007, 46, 389-392; Angew. Chem. 2007, 119, 393-396.

10. J.-W. Xie, L. Yue, D. Xue, X.-L.Ma, Y.-C. Chen, Y. Wu, J. Zhu, and J.-G. Deng, "Organocatalytic and Direct Asymmetric Vinylogous Michael Addition of α,α- Dicyan-oolefins to α,β-Unsaturated Aldehyde", Chem. Commun., 2006, 1563-1565.

代表性科研项目

1.2012.07-2012.12,浙江省科技厅-基于手性胺出发的新型催化剂的合成及应用(2009R50020-13);

2.2013.01-2016.12,国家自然科学基金面上项目-基于1,3-二羰基化合物的串联反应高选择性合成杂环化合物的研究(21272214);

3.2010.01-2012.12,国家自然科学基金青年基金-新颖手性有机催化剂在不对称催化1,3-质子迁移和三氟甲基化反应的应用(20902083);

4.2010.01-2011.12,浙江省自然科学基金-有机催化不对称合成光学纯的三氟甲基化合物(Y4090082)。

成果获奖:

1.基于羰基化合物高选择性合成杂环化合物的研究;浙江省人民政府;浙江省科学技术奖三等奖;谢建武(排名1/6);2013年;

2.中国科学院院长优秀奖;中国科学院;优秀奖;谢建武;2007年;

3.中国科学院西部学子奖;中国科学院;一等奖;谢建武;2007年;

4.中国科学院西部学子奖;中国科学院;二等奖;谢建武;2006年。

学术报告

1.2009.8,在中国化学会第六届全国有机化学学术会议作学术报告《有机催化不对称合成具有生物活性的吡咯及苯并吡喃衍生物》;

2.2010.6,在中国化学会第27届学术年会学术会议作学术报告《有机催化不对称合成一些杂环化合物》。


近三年教学情况

为本科生主讲课程有《有机化学》、《有机合成与路线设计》、指导本科生论文25余篇;为研究生开设《高等有机化学》、《不对称合成》等课程,指导培养硕士研究生7名。


Profile

Jian-Wu Xie (born December 27, 1978) is a professor of organic chemistry.


Education Background

B.Sc. Guangxi Normal University (2001)

M.Sc. Guangxi Normal University (2004)

Ph.D. Chinese Academy of Sciences (2007)

Postdoctoral fellow, Kyoto University (2008)


Work Experiences

Professor of Department of Chemistry and Life Sciences, Zhejiang Normal University (2008-present)


Honorable Titles and Awards

1. Middle-aged and Young Academic Leaders in University, Zhejiang (2013)

2. Excellent Talents of the “151” Talents Project in New Century, Zhejiang (2009)

3. Key Teachers of Zhejiang Normal University (2008)


Research Field and Achievements

1. Development of new enantio- and stereoselective synthetic methods.

2. Synthetic studies on multi-functional heterocyclic compounds and their biological activity.

Representative Works

1. T. Shi, Z. Guo, H. Yu, J.-W. Xie*, Y. Zhong, W. Zhu*,Highly Atom-Economic Synthesis of Optically Active Warfarin Anticoagulant over a Chiral MOF Organocatalyst, Adv. Synth. Catal., 2013, 355, 2538-2543.

2.Z.-W. Guo, X.-S. Li, W.-D. Zhu, J.-W. Xie,* Construction of Chiral Multi-functionalized Polyheterocyclic Benzopyran Derivatives by Using an Asymmetric Organocatalytic Domino Reaction, Eur. J. Org. Chem., 2012, 6924–6932.

3. Y.-R. Zhang, J.-W. Xie*, X.-J. Huang, W.-D. Zhu*, Construction of Functionalized 2,3-Dihydro-1,4-Benzoxazines via [5 + 1] Annulations of 2-Halo-1,3-Dicarbonyl Compounds with Imines, Org. Biomol. Chem. 2012, 10, 6554-6561.

4. P. Li, B.-T. Teng, F.-G. Jin, X.-S. Li, W.-D. Zhu, J.-W. Xie*, Synthesis of Functionalized 2,3-Dihydroisoxazoles by Domino Reactions in Water and Unexpected Ring-Opening Reactions of 2,3-Dihydroisoxazoles, Org. Biomol. Chem., 2012, 10, 244-247.

5. Q.-B. Li, F.-T., Zhou, Z.-G. Liu, X.-F. Li, W.-D. Zhu, J.-W. Xie*, K2CO3-Promoted Domino Reactions: Construction of Functionalized 2,3-Dihydrobenzofurans and Clofibrate Analogues, J. Org. Chem. 2011, 76, 7222-7228.

6. L.-P Fan, P. Li, X.-S. Li, D.-C. Xu, M.-M. Ge, W.-D. Zhu, J.-W. Xie*, Facile Domino Access to Chiral Mono-, Bi- and Tricyclic 2,3-Dihydrofurans, J. Org. Chem. 2010, 75, 8716-8719.

7. J.-W. Xie*, X. Huang, L.-P. Fan, D.-C. Xu, X.-S. Li, H. Su, Y.-H. Wen, “Efficient Method for  the Synthesis of Optically Active 2-Amino-2-Chromene Derivatives via One-Pot Tandem Reaction”, Adv. Synth. Catal., 2009, 351, 3077-3082.

8. J.-W. Xie, L. Yue, W. Chen, W. Du, J. Zhu, J.-G. Deng, and Y.-C. Chen, "Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to, α,β-Unsaturated Ketones", Org. Lett., 2007, 9, 413-415.

9. J.-W. Xie, W. Chen, R. Li, M. Zeng, W. Du, L. Yue, Y.-C. Chen, Y. Wu, J. Zhu, and J.-G. Deng, "Highly Asymmetric Michael Addition to a,β-Unsaturated Ketones Catalyzed by 9-Amino-9-deoxyepiquinine", Angew. Chem. Int. Ed, 2007, 46, 389-392; Angew. Chem. 2007, 119, 393-396.

10. J.-W. Xie, L. Yue, D. Xue, X.-L.Ma, Y.-C. Chen, Y. Wu, J. Zhu, and J.-G. Deng, "Organocatalytic and Direct Asymmetric Vinylogous Michael Addition of α,α- Dicyan-oolefins to α,β-Unsaturated Aldehyde", Chem. Commun., 2006, 1563-1565.

Research Projects

1. National Natural Science Foundation of China (20902083)

2. National Natural Science Foundation of China (21272214)

3. Natural Science Foundation of Zhejiang Province (Y4090082)

4. Science and Technology Foundation of Zhejiang Province (2009R50020-13)

Awards

1. Zhejiang Province Science and Technology Awards (3rd Class, No.1) (2013)

2. Chinese Academy of Sciences Presidential Scholarship (2007)

3. Postgraduate Scholarship of Western Students, Chinese Academy of Sciences (2006, 2007)


Teaching and Supervision during Last 3 Years

《Organic Chemistry》for undergraduate students in chemistry;

《Advanced Organic Chemistry》graduate students in chemistry.


Contact

Email: xiejw@zjnu.cn