朱钢国

作者:来源:发布时间:2017-04-14

个人简介

朱钢国,男,1978年10月生,浙江省金华市金东区人,现为浙江师范大学化学与生命科学学院教授、硕士生导师


学习经历

1996.9-2000.7   浙江师范大学化学系获理学学士,化学专业

2000.9-2005.7   中科院上海有机化学研究所获理学博士,有机化学专业

2005.9-2007.10  美国普渡大学诺贝尔奖得主Negishi小组博士后研究

2007.11-2008.10 美国印第安纳大学化学系博士后研究


工作简历

2008.12-至今   浙江师范大学化学与生命科学学院任教,教授(2011.12)


人才梯队、荣誉

浙江省“151”人才第三层次培养对象(2009.6)

浙江省高校中青年学科带头人(2013.6)


研究领域及成果

主要从事金属有机化学专业领域的研究,发表Chem. Commun.Org. Lett.Chem. Eur. J.Adv. Synth. Catal.J. Org. Chem.等SCI论文30多篇,著作章节1篇,其中以通讯作者或第一作者发表影响因子大于4论文19篇。

代表性论文、论著

(详细论文目录见: http://sky.zjnu.net.cn/E_ReadNews.asp?NewsID=1474)

1. Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.; Zhu, G.* Chem. Commun. 2013, 49, 7650-7652.

2. A Regio- and Stereoselective Entry to ,-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzuki–Miyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.; Zhu, G.* J. Org. Chem. 2013, 78, 9815-9821.

3. Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3,4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.; Zhu, G.* J. Org. Chem. 2013, 78, 10894-10901.

4. Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides. Zhu, G.*; Chen, D.; Wang, Y.; Zheng, R. Chem. Commun. 2012, 48, 5796-5798.

5. Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling of N-Alkynyl tert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.; Zhu, G.* J. Org. Chem. 2012, 77,9871-9877.

6. Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)--chloroenol ethers. Cai, H.; Yuan, Z.; Zhu, W.; Zhu, G.* Chem. Commun. 2011, 47, 8682-8684.

7. Palladium-catalyzed highly regio- and stereoselective synthesis of (1E)- or (1Z)-1,2-dihalo-1,4-dienes via haloallylation of alkynyl halides. Chen, X.; Kong, W.; Cai, H.; Kong, L.; Zhu, G.* Chem. Commun. 2011, 47, 2164-2166.

8. Palladium-Catalyzed Dienylation of Haloalkynes Using 2,3-Butadienyl Acetates: A Facile Access to (1Z)-1,2-Dihalo-3-vinyl-1,3-dienes. Chen, D.; Chen, X.; Lu, Z.; Cai, H.; Shen, J.; Zhu, G.* Adv. Synth. Catal. 2011, 353, 1474-1478.

9. Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides. Lu, Z.; Kong, W.; Yuan, Z.; Zhao, X.; Zhu. G.* J. Org. Chem. 2011, 76, 8524-8529.

10. Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Highly Regio- and Stereoselective Synthesis of (Z)--Haloenol Acetates. Chen, X.; Chen, D.; Lu, Z.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 6338-6343.

代表性科研项目

1.2012-2015,国家自然科学基金面上项目-“基于1,2-双官能团化烯烃的偶联反应选择性合成多取代烯烃”;

2.2012-2014,浙江省杰出青年基金-“1-卤-1-硫代烯烃的立体选择性合成及其三取代烯烃的构建”;

3.2010-2012,国家自然科学基金青年项目-“偶极烯丙基钯的环加成反应研究”,已结题;

4.2010-2012,浙江省钱江人才计划项目-“抗禽流感药物达菲的合成工艺研究”,已结题。

成果获奖

“杂原子取代炔烃的亲核钯化反应方法学研究”获2012年浙江省高等学校科研成果奖一等奖。


近三年教学情况

为本科生主讲课程有《有机化学》、《有机化学实验》、《有机合成化学》,指导本科生论文10余篇;为研究生开设《金属有机化学》等课程,指导培养硕士研究生4名,获校优秀硕士论文2篇。


Profile

Department of Chemistry

Zhejiang Normal University

688 Yingbin Road, Jinhua

Zhejiang, China, 321004


Education Background

1996-2000  Zhejiang Normal University, B.S.;

2000-2005  Shanghai Institute of Organic Chemistry, CAS, Ph.D., advisor: Prof. Zhaoguo Zhang;

2005-2007  Purdue University, postdoctor, advisor: Ei-ichi Negishi;

2007-2008  Indiana University, postdoctor, advisor: Z. Aron;


Work Experiences

2009-present  Zhejiang Normal University, professor of chemistry.


Research Field and Achievements

Our research program is directed at developing new synthetic useful reactions, and then demonstrating how these reactions can be utilized for complex molecules synthesis. The current topics include: (1) the development of novel regio- and stereoselective reactions; (2) the effective assembly of tri- or tetrasubstituted alkenes; (3) the synthesis of bioactive compounds.

Representative Works

http://sky.zjnu.net.cn/E_ReadNews.asp?NewsID=1474

1. Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.; Zhu, G.* Chem. Commun. 2013, 49, 7650-7652.

2. A Regio- and Stereoselective Entry to ,-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzuki–Miyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.; Zhu, G.* J. Org. Chem. 2013, 78, 9815-9821.

3.Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3, 4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.; Zhu, G.* J. Org. Chem. 2013, 78, 10894-10901.

4. Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides. Zhu, G.*; Chen, D.; Wang, Y.; Zheng, R. Chem. Commun. 2012, 48, 5796-5798.

5. Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling of N-Alkynyl tert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.; Zhu, G.* J. Org. Chem. 2012, 77,9871-9877.

6. Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)--chloroenol ethers. Cai, H.; Yuan, Z.; Zhu, W.; Zhu, G.* Chem. Commun. 2011, 47, 8682-8684.

7. Palladium-catalyzed highly regio- and stereoselective synthesis of (1E)- or (1Z)-1,2-dihalo-1,4-dienes via haloallylation of alkynyl halides. Chen, X.; Kong, W.; Cai, H.; Kong, L.; Zhu, G.* Chem. Commun. 2011, 47, 2164-2166.

8. Palladium-Catalyzed Dienylation of Haloalkynes Using 2,3-Butadienyl Acetates: A Facile Access to (1Z)-1,2-Dihalo-3-vinyl-1,3-dienes. Chen, D.; Chen, X.; Lu, Z.; Cai, H.; Shen, J.; Zhu, G.* Adv. Synth. Catal. 2011, 353, 1474-1478.

9. Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides. Lu, Z.; Kong, W.; Yuan, Z.; Zhao, X.; Zhu. G.* J. Org. Chem. 2011, 76, 8524-8529.

10.Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Highly Regio- and Stereoselective Synthesis of (Z)--Haloenol Acetates. Chen, X.; Chen, D.; Lu, Z.; Kong, L.; Zhu, G.* J. Org. Chem. 2011, 76, 6338-6343.

Research Projects

NSFC (21172199 and 20902084)

NSF of Zhejiang Province (LR12B02001)

Science Technology Department of Zhejiang Province (2010R10016).

Awards

Excellent Research Achievements in Universities of Zhejiang, First Prize, 2012.


Teaching and Supervision during Last 3 Years

Organic Chemistry (undergraduate); Organometallic Chemistry (graduate).


Contact

Tel: 86-579-82283702

E-mail: gangguo@zjnu.cn